Neurobiology of Disease Effects of Early Life Stress on [C]DASB Positron Emission Tomography Imaging of Serotonin Transporters in Adolescent Peer- and Mother-Reared Rhesus Monkeys
نویسندگان
چکیده
Masanori Ichise,1 Douglass C. Vines,1 Tami Gura,2 George M. Anderson,3 Stephen J. Suomi,4* J. Dee Higley,2* and Robert B. Innis1* 1Molecular Imaging Branch, National Institute of Mental Health, Bethesda, Maryland 20892, 2Laboratory of Clinical Studies–Primate Unit, Division of Intramural Clinical and Biological Research, National Institute on Alcohol Abuse and Alcoholism, Poolesville, Maryland 20837, 3Departments of Child Psychiatry and Laboratory Medicine, Yale University School of Medicine, New Haven, Connecticut 06510, and 4Laboratory of Comparative Ethology, National Institute of Child and Human Development, National Institutes of Health Animal Center, Poolesville, Maryland 20837
منابع مشابه
Early-life stress induces long-term morphologic changes in primate brain.
CONTEXT Traumatic experiences in early childhood are associated with increased risk of developing stress-related disorders, which are linked to structural brain abnormalities. However, it is unclear whether these volumetric brain changes are present before disease onset or reflect the consequences of disease progression. OBJECTIVE To identify structural abnormalities in the nonhuman primate b...
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